Synthetic Nicotine

NicSynSelect 3.0

Ultra-clean, ultra-pure, 100% Synthetic S-Nicotine


Nicotine exists as two enantiomers: (S) -Nicotine and (R)-Nicotine. In natural nicotine (derived from tobacco), the ratio is 99% (S) -Nicotine to 1% (R)-Nicotine, when nicotine is synthesized in a lab, it is a 50:50 racemic (S):(R)-Nicotine mixture.

As only (S)-Nicotine is bioavailable and bioactive in humans, Alchem NicSelect™ employs novel technologies to isolate and purify (S)-Nicotine to our NicSelect™ Nicotine 3.0 purity standard and achieve the cleanest synthetic nicotine available.

Many companies claim to offer synthetic nicotine, yet often, they provide tobacco-derived nicotine or racemic mixtures. The only reliable method to distinguish between them is through laboratory tests. NicSynSelect 3.0 undergoes rigorous testing, ensuring its 100% synthetic origin is guaranteed.

Our verification process includes:

Radiocarbon analysis: This method distinguishes synthetic nicotine from tobacco-derived nicotine.

Chiral chromatography: By separating optical isomers (enantiomers), this technique quantifies the relative (or absolute) quantities of (S) and (R)-Nicotine.

Nicotine Impurity Profile: Mirroring the renowned quality of NicSelect™ Nicotine 3.0, our synthetic nicotine is ultra-clean, ultra-pure and ultra-stable, with exceptional organoleptic properties and consistent from batch-to-batch.

#1 choice and trusted by 70% of e-liquid and pouch manufacturers globally

Batch-to-batch consistent, clear like water, organoleptically NOTES© perfect

Zero impurities (EP/USP)

cGMP and TPD compliant, REACH registered and US FDA TPMF filled

cGMP and TPD compliant, REACH registered and US FDA TPMF filled

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