Pharmaceutical
Nicotine

In addition to manufacturing high-quality nicotine for the vape industry Alchem International produces pharmaceutical-grade liquid nicotine and nicotine salts and complexes supported by comprehensive documentation (cGMP, EU written confirmations and DMFs) for use in registered Nicotine Replacement Therapies (NRT).

Production is made according to the international “gold standard” ICH cGMP in certified facilities and supported by Drug Master Files (DMFs) and Certificates of Suitability (CEPs) granted by the EDQM for medicinal registration.

Alchem International is regularly audited by major ministries of health from regulated markets (EDQM, US FDA, COOPRIS, WHO etc.) and provides renowned service and technical support.

Pure nicotine EP/USP

Used in nicotine patches, nicotine sprays, white snus and nicotine gum formulations in treating nicotine dependence in order to eliminate smoking and the damage it does to health. Controlled levels of nicotine are given to patients through gums, dermal patches, lozenges, electronic cigarettes or nasal sprays.

Nicotine Ditartrate Dihydrate EP

Used primarily in nicotine lozenges and white snus due to the improved oral solubility and bioavailability of nicotine salts. For this reason, lozenges are particularly efficient at helping with nicotine cravings and withdrawal symptoms as most of the nicotine contained in the lozenge is rapidly absorbed into the bloodstream and not lost.

Nicotine resinate EP (Nicotine polacrilex USP)

Used in nicotine chewing gum and lozenges and white snus formulations. Nicotine resinate (polacrilex) is the form of nicotine found in oral products used to help people quit smoking cigarettes. The nicotine is bound to an ion-exchange resin in these products to facilitate controlled release and aid in the absorption through the mucous membranes in the mouth. These products can provide a means to ease nicotine withdrawal symptoms and overcome the addiction to smoking.

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