Nicotine
Applications

Alchem, leading the way

Alchem International is a leading global manufacturer of natural nicotine, nicotine salts and nicotine complexes for use in tobacco substitutes, including e-cigarettes, white snus, nicotine patches, nicotine gums and nicotine lozenges.

E-cigarettes

Since their introduction in 2006, e-cigarettes have reached an estimated global market value of 19.3 billion USD in 2019. With their exceptional growth and popularity, e-cigarettes have posed a challenge to other smoking cessation products as well as to the tobacco cigarette industry. Their rapid growth is expected to continue as consumers chose to avoid tobacco products. As of 2016, with the application of the European TPD (tobacco Product Directive), the e-liquid and e-cigarette market is more regulated to ensure a consistent product quality and provide a reference for European consumers. In the US, all nicotine products are now regulated under the US FDA tobacco Deeming Regulations with the requirement to file PMTAs (pre-market tobacco approval).

Alchem International NicSelect™ liquid nicotine is manufactured to the highest possible quality standards under pharmaceutical cGMP conditions and subject to rigorous analytical controls to ensure the highest purity and lowest impurity levels. This ensures compliance with even the strictest regulations as well as guarantees outstanding quality and consistency. We are REACH and TPD compliant for Europe and have filed a tobacco Product Master File (TMPFs) for Nicotine USP with the US FDA to support our customers tobacco Product Master Files (TMPFs) applications.

Patches, gums & lozenges

The global market size of nicotine replacement therapy (NRT) products reached just above 3 billion USD in 2014 – an increase of almost 300% in a decade. The most common forms are gums, inhalers, lozenges, nasal sprays, skin patches. Today, the market size is similar to those of e-cigarettes and is still growing strongly as new delivery devices are developed and consumers are looking for alternatives to their current tobacco products.

Alchem International produces pharmaceutical-grade liquid nicotine and nicotine powder complexes specifically for these applications in cGMP certified facilities and supported by Drug Master Files (DMFs) for medicinal registration.

White snus

White snus is a modern take on loose snus or tobacco pouches that have been popular for many years in Scandinavia, East Europe and Russia.
White snus is a cleaner version of chewing tobacco, tobacco snus or tobacco snus pouches with nicotine on a carrier line like microcrystalline cellulose or a powdered nicotine such nicotine bitartrate dihydrate or nicotine salicylate contained a small pouch offering a dryer, less drip and a longer-lasting flavor release that remains completely white before, during and after use.

Alchem International NicSelect™ nicotine powders are manufactured under pharmaceutical cGMP conditions and we are REACH compliant for Europe and have filed a tobacco Product Master File (TMPFs) for Nicotine bitartrate dihydrate with the US FDA to support our customers tobacco Product Master File (TMPFs) applications.

     

Product

 

Quality

 

Application

 

Regulatory

 

Documentation

NicSelect™ Nicotine EP / USP Premium grade pure nicotine cGMP Pharma USDMF, EDMF Technical data sheet MSDS, cGMP certificate
NicSelect™ Nicotine EP / USP Premium grade pure nicotine cGMP E-liquids US FDA, TPMF filed, REACH, TPD Technical data sheet MSDS, cGMP certificate
Nicselect™ Nicotine bases Standard bases: 72mg/ml, 100 mg/ml Custom bases: 6,12,18mg/ml Propylene glycol(PG) or Vegetable Glycerin(VG) bases Premium grade nicotine bases ‘ready to flavour’ cGMP E-liquids REACH, TPD Technical data sheet MSDS, cGMP certificate
Nicotine Ditartrate Dihydrate EP A pure crystalline salt of nicotine in powder format cGMP Pharma USDMF, EDMF Technical data sheet MSDS, cGMP certificate
NEW Nicotine Ditartrate salt powder A pure crystalline salt of nicotine in powder format cGMP Snus and liquids DIY home Mixing from powder form US FDA, TPMF filed, REACH Technical data sheet MSDS, cGMP certificate
Tobacco Absolute An original base flavour for a real cigarette taste cGMP E-liquids   Technical data sheet MSDS, cGMP certificate
Nicotine Resinate / Nicotine Polacrilex USP/EP A nicotine ion-exchange resin complex for controlled nicotine release to the body cGMP Pharma USDMF, EDMF Technical data sheet MSDS, cGMP certificate
NEW Nicotine Salts: Velvet, Smooth, Rush, Chill, Silver Premium grade nicotine salt bases ‘ready to flavour cGMP E-liquids TPD Technical data sheet MSDS, cGMP/ISO certificate
NEW Nicotine Salicylate salt powders A pure crystalline salt of nicotine in powder format cGMP Snus and liquids DIY home Mixing from powder form TPD, REACH Technical data sheet MSDS, cGMP certificate
NEW Nicotine Ortho-Salicylate powder A pure crystalline salt of nicotine in powder format cGMP Snus and liquids DIY home Mixing from powder form TPD, REACH Technical data sheet MSDS, cGMP certificate

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